Papers
2024
- Rybnikář M., Malaník M., Šmejkal K., Švajdlenka E., Shpet P., Babica P., Dall'Acqua S., Smištík O., Jurček O., Treml J.*: Dibenzocyclooctadiene Lignans from Schisandra chinensis with Anti-inflammatory Effects. International Journal of Molecular Sciences (accepted)
- Raptová P., Skočková V., Babica P., Sovadinová I., Sychrová E., Vídeňská P., Šplíchalová P., Vašíček O., Šindlerová L.* (2024): Cyanobacterial water bloom lipopolysaccharides induce pro-inflammatory processes in keratinocytes in vitro. Environmental Toxicology and Pharmacology 105:104342. https://doi.org/10.1016/j.etap.2023.104342 Link PubMed
- Skočková V., Raptová P., Pospíchalová K., Sovadinová I., Sychrová E., Smutná M., Hilscherová K., Babica P., Šindlerová L.* (2024): Cyanobacterial harmful bloom lipopolysaccharides: pro-inflammatory effects on epithelial and immune cells in vitro. Archives of Toxicology 98:481–491. https://doi.org/10.1007/s00204-023-03644-8 Link (Open Access) PubMed
- Chowdhury R. R., Rose S., Ezan F., Sovadinová I., Babica P., Langouet S.* (2024): Hepatotoxicity of cyanotoxin microcystin-LR in human: insights into mechanisms of action in the 3D culture model Hepoid-HepaRG. Environmental Pollution 342:123047, https://doi.org/10.1016/j.envpol.2023.123047 Link (Open Access) PubMed
2023
- Bajard L., Vespalcová H., Negi C., Kohoutek J., Bláha L., Sovadinová I.* (2023): Anti-androgenic activity of novel flame retardants in mixtures: Newly identified contribution from tris(2,3-dibromopropyl) isocyanurate (TDBP-TAZTO). Chemosphere 341:140004. https://doi.org/10.1016/j.chemosphere.2023.140004 Link (Open Access) PubMed
- Audebert M.*, Azqueta A., Babica P., Benfenati E., Bortoli S., Bouwman P., Braeuning A., Burgdorf T., Coumoul X., Debizet K., Dusinska M., Ertych N., Fahrer J., Fetz V., Le Hégarat L., López De Cerain A., Heusinkveld H., Hogeveen K., Jacobs M., Luijten M., Raitano G., Recoules C., Rundén-Pran E., Saleh M., Sovadinova I., Stampar M., Thibol L., Tomkiewicz C., Vettorazzi A., Van De Water B., El Yamani N., Zegura B., Oelgeschläger M.* (2023): New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogensa PARC project. Frontiers in Toxicology 5:1220998. https://doi.org/10.3389/ftox.2023.1220998 Link (Open Access) PubMed
- Priya I., Virmani I., Pragya B., Goswami R. K., Singh B., Sharma J. G., Giri B.* (2023): Role of microbial phytases in improving fish health. Reviews in Aquaculture 15:1480–1500. https://doi.org/10.1111/raq.12790 Link
- Součková K.*, Jasík M., Sovadinová I., Sember A., Sychrová E., Konieczna A., Bystrý V., Dyková I., Blažek R., Lukšíková K., Pavlica T., Jankásek M., Altmanová M., Žák J., Zbončáková A., Reichard M., Slabý O. (2023): From fish to cells: Establishment of continuous cell lines from embryos of annual killifish Nothobranchius furzeri and N. kadleci. Aquatic Toxicology 259:106517. https://doi.org/10.1016/j.aquatox.2023.106517 Link PubMed
- Skočková V., Vašíček, O., Sychrová E., Sovadinová I., Babica P., Šindlerová, L.* (2023): Cyanobacterial harmful bloom lipopolysaccharides Induce pro-Inflammatory effects in immune and intestinal epithelial cells in vitro. Toxins 15(3):169. https://doi.org/10.3390/toxins15030169 Link (Open Access) PubMed
- Labohá P., Sychrová E., Brózman O., Sovadinová I., Bláhová L., Prokeš R., Ondráček J., Babica P.* (2023): Cyanobacteria, cyanotoxins and endotoxins in aerosols from inland freshwater bodies and their effects on human bronchial cells. Environmental Toxicology and Pharmacology 98:104073. https://doi.org/10.1016/j.etap.2023.104073 Link PubMed
- Bajard L., Adamovsky O., Audouze K. , Baken K., Barouki R., Beltman J. B., Beronius A., Bonefeld-Jørgensen E. C., Cano-Sancho G., de Baat M. L., Di Tillio F., Fernández M. F., FitzGerald R. E., Gundacker C., Hernández A. F., Hilscherova K., Karakitsios S., Kuchovska E., Long M., Luijten M., Majid S., Marx-Stoelting P., Mustieles V., Negi C. K., Sarigiannis D., Scholtz S., Sovadinova I., Stierum R., Tanabe S., Tollefsen K. E., van den Brand A. D., Vogs C., Wielsøe M., Wittwehr C., Blaha L.* (2023): Application of AOPs to assist regulatory assessment of chemical risks – Case studies, needs and recommendation. Environmental Research 217:114650. https://doi.org/10.1016/j.envres.2022.114650 Link (Open Access) PubMed
- Virmani I., Oteo A., Dunn M., Vidler D., Roper C., Officer J., Hardy G., Dargan P. I., Eddleston M., Cooper J. G., Hill S. L., Macfarlane R., Keating L., Haden M., Hudson S., Thomas S. H. L.* (2023): Accuracy of substance exposure history in patients attending emergency departments after substance misuse; a comparison with biological sample analysis. Clinical Toxicology 61(1):39-46. https://doi.org/10.1080/15563650.2022.2131566 Link (Open Access) PubMed
2022
- Takahashi H., Sovadinová I., Yasuhara K., Vemparala S., Caputo G. A.*, Kuroda, K.* (2022): Biomimetic antimicrobial polymers—Design, characterization, antimicrobial, and novel applications. WIREs Nanomedicine and Nanobiotechnology e1866. https://doi.org/10.1002/wnan.1866 Link (Open Access) PubMed
- Sehnal L., Smutná M., Bláhová L., Babica P., Šplíchalová P., Hilscherová K.* (2022): The origin of teratogenic retinoids in cyanobacteria. Toxins 14(9), 636. https://doi.org/10.3390/toxins14090636 Link (Open Access) PubMed
- Bernal K., Charbel T., Erradhouani C., Boronat-Belda T., Gaillard L., Kassir S., Le Mentec H., Martin-Chouly C., Podechard N., Lagadic-Gossmann D., Langouet S., Brion F., Knoll-Gellida A., Babin P. J., Sovadinova I., Babica P., Andreau K., Barouki R., Vondracek J., Alonso-Magdalena P., Blanc E., Kim M.-J.*, Coumoul X.* (2022): Combinatorial pathway disruption as an approach to delineate metabolic impacts of endocrine disruptors. FEBS Letters 596(24):3107-3123. https://doi.org/10.1002/1873-3468.14465 Link (Open Access) PubMed
- Sychrová E., Yawer A., Labohá P., Basu A., Dydowiczová A., Virmani I., Babica P., Sovadinová I.* (2022): Testicular toxicity of environmentally relevant endocrine-disrupting chemicals in 2D and 3D in vitro models of Leydig cells. Environmental Toxicology and Pharmacology 93:103869. https://doi.org/10.1016/j.etap.2022.103869 Link PubMed
- Durník R., Šindlerová L., Babica P., Jurček O.* (2022): Bile acids transporters of enterohepatic circulation for targeted drug delivery. Molecules 27(9):2961. https://doi.org/10.3390/molecules27092961 Link (Open Access) PubMed
- Yawer A., Sychrová E., Raška J., Babica P., Sovadinová I.* (2022): Endocrine-disrupting chemicals affect Sertoli TM4 cell functionality through dysregulation of gap junctional intercellular communication in vitro. Food and Chemical Toxicology 164:113004. https://doi.org/10.1016/j.fct.2022.113004 Link PubMed
- Tanabe S.*, O'Brien J., Tollefsen K. E., Kim Y., Chauhan V., Yauk C., Huliganga E., Rudel R. A., Kay J. E., Helm J. S., Beaton D., Filipovska J., Sovadinova I., Garcia-Reyero N., Mally A., Søs Poulsen S., Delrue N., Fritsche E., Luettich K., La Rocca C., Yepiskoposyan H., Klose J., Høgh Danielsen P., Esterhuizen M., Raun Jacobsen N., Vogel U., Gant T. W., Choi I., FitzGerald R. (2022): Reactive Oxygen Species in the Adverse Outcome Pathway Framework: Toward Creation of Harmonized Consensus Key Events. Frontiers in Toxicology 4:887135. https://doi.org/10.3389/ftox.2022.887135 Link (Open Access) PubMed
- Tanabe S.*, Beaton D., Chauhan V., Choi I., Danielsen P. H., Delrue N., Esterhuizen M., Filipovska J., FitzGerald R., Fritsche E., Gant T., Garcia-Reyero N., Helm J., Huliganga E., Jacobsen N., Kay J. E., Kim Y.-J., Klose J., La Rocca C., Luettich K., Mally A., O’Brien J., Poulsen S. S., Rudel R. A., Sovadinova I., Tollefsen K. E., Vogel U., Yepiskoposyan H., Yauk C. (2022): Report of the 1st and 2nd Mystery of Reactive Oxygen Species Conferences. ALTEX - Alternatives to animal experimentation 39(2):336–338. https://doi.org/10.14573/altex.2203011 Link PubMed
- Toušová Z. Priebojová J., Javůrek J., Večerková J., Lepšová-Skácelová O., Sychrová E., Smutná M., Hilscherová K.* (2022): Estrogenic and retinoid-like activity in stagnant waters with mass occurrence of water blooms. Science of The Total Environment 852(15):158257. https://doi.org/10.1016/j.scitotenv.2022.158257 Link PubMed
- Schneider M.*, Grossi M. F., Gadara D. C., Spáčil Z., Babica P., Bláha L. (2022): Treatment of cylindrospermopsin by hydroxyl and sulfate radicals: Does degradation equal detoxification? Journal of Hazardous Materials 424(B), 127447. https://doi.org/10.1016/j.jhazmat.2021.127447 Link (Open Access) PubMed
2021
- Martens M., Stierum R., Schymanski E.L., Evelo C.T., Aalizadeh R., Aladjov H., Arturi K., Audouze K., Babica P., Berka K., Bessems J., Blaha L., Bolton E. E., Cases M., Damalas D. E., Dave K., Dilger M., Exner T., Geerke D. P., Grafström R., Gray A., Hancock J. M., Hollert H., Jeliazkova N., Jennen D., Jourdan F., Kahlem P., Klanova J., Kleinjans J., Kondic T., Kone B., Lynch I., Maran U., Cuesta S. M., Ménager H., Neumann S., Nymark P., Oberacher H., Ramirez N., Remy S., Rocca-Serra P., Salek R. M., Sallach B., Sansone S.-A., Sanz F., Sarimveis H., Sarntivijai S., Schulze T., Slobodnik J., Spjuth O., Tedds J., Thomaidis N., Weber R. J. M., van Westen G. J. P., Wheelock C. E., Williams A. J., Witters H., Zdrazil B., Županič A., Willighagen E. L.* (2021): ELIXIR and Toxicology: a community in development. F1000 Research 10(ELIXIR):1129 https://doi.org/10.12688/f1000research.74502.1 Link (Open Access)
- Bláhová L., Sehnal L., Lepšová-Skácelová O., Szmucová V. Babica P., Hilscherová K., Teikari J., Sivonen K., Bláha L.* (2021): Occurrence of cylindrospermopsin, anatoxin-a and their homologs in the Czech Republic freshwaters – taxonomical, analytical, and molecular approaches. Harmful Algae 108:102101 https://doi.org/10.1016/j.hal.2021.102101 Link PubMed
- Sovadinová I., Upham B.L., Trosko J. E., Babica P.* (2021): Applicability of scrape loading-dye transfer assay for non-genotoxic carcinogen testing. International Journal of Molecular Sciences 22(16):8977. https://doi.org/10.3390/ijms22168977 Link (Open Access) PubMed
- Sovadinová I., Kuroda K.*, Palermo E.* (2021): Unexpected enhancement of antimicrobial polymer activity against Staphylococcus aureus in the presence of fetal bovine serum. Molecules 26(15):4512. https://doi.org/10.3390/molecules26154512 Link (Open Access) PubMed
- Mikula P., Mlnaříková M., Nadres E., Takahashi H., Babica P., Kuroda K., Bláha L., Sovadinová I.* (2021): Synthetic biomimetic polymethacrylates: Promising platform for design of anti-cyanobacterial and anti-algal agents. Polymers 13(7):1025. https://doi.org/10.3390/polym13071025 Link (Open Access) PubMed
2020
- Čtveráčková L., Jančula D., Raška J., Babica P., Sovadinová I.* (2020): Structure-dependent effects of phthalates on intercellular and intracellular communication in liver oval cells. International Journal of Molecular Sciences 21(17):6069. https://doi.org/10.3390/ijms21176069 Link (Open Access) PubMed
- Basu A., Dydowiczová A., Trosko J.E., Bláha L., Babica P.* (2020): Ready to go 3D? A semi-automated protocol for microwell spheroid arrays to increase scalability and throughput of 3D cell culture testing. Toxicology Mechanisms and Methods 30(8):590-604. https://doi.org/10.1080/15376516.2020.1800881 Link PubMed
- Vašíček O., Hájek J., Bláhová L., Hrouzek P., Babica P., Kubala L., Šindlerová, L.* (2020): Disruptive and inflammatory effects of cyanobacterial lipopeptides puwainaphycin and minutissamides in Caco-2 human intestinal barrier model. Harmful Algae 96:101849. https://doi.org/10.1016/j.hal.2020.101849 Link PubMed
- Brózman O., Kubickova B., Babica P., Labohá P.* (2020): Microcystin-LR does not alter cell survival and intracellular signaling in human bronchial epithelial cells. Toxins 12(3), 165. https://doi.org/10.3390/toxins12030165 Link (Open Access) PubMed
- Dydowiczowá A., Brózman O., Babica P., Sovadinová I.* (2020): Improved multiparametric scrape loading-dye transfer assay for a simultaneous high-throughput analysis of gap junctional intercellular communication, cell density and viability. Scientific Reports 10:730. https://doi.org/10.1038/s41598-020-57536-3 Link (Open Access) PubMed
2019
- Kubickova B., Babica P., Hilscherová K., Šindlerová L.* (2019): Effects of cyanobacterial toxins on the human gastrointestinal tract and the mucosal innate immune system. Environmental Sciences Europe 31:31,1-27. https://doi.org/10.1186/s12302-019-0212-2 Link (Open Access)
- Moosová Z. #, Šindlerová L.#, Ambrůzová B., Ambrožová G., Vašíček O., Velki M., Babica P., Kubala L.* (2019): Lipopolysaccharides from Microcystis cyanobacteria-dominated water bloom and from laboratory cultures trigger human immune innate response. Toxins 11(4):218. https://doi.org/10.3390/toxins11040218 Link (Open Access) PubMed
- Jaša L., Sadílek J., Kohoutek J., Straková L., Maršálek B., Babica P.* (2019): Application of passive sampling for sensitive time-integrative monitoring of cyanobacterial toxins microcystins in drinking water treatment plants. Water Research 153:108-120. https://doi.org/10.1016/j.watres.2018.12.059 Link PubMed
- Kubickova B., Labohá P., Hildebrandt J.-P., Hilscherová K., Babica P.* (2019): Effects of cylindrospermopsin on cultured immortalized human airway epithelial cells. Chemosphere 220:620-628. https://doi.org/10.1016/j.chemosphere.2018.12.157 Link (Open Access) PubMed
- Váňová T., Raška J., Babica P.; Sovadinová I., Kunová-Bosaková M., Dvořák P., Bláha L., Rotrekl V.* (2019): Freshwater cyanotoxin cylindrospermopsin has detrimental stage-specific effects on hepatic differentiation from human embryonic stem cells. Toxicological Sciences 168(1):241-251. https://doi.org/10.1093/toxsci/kfy293 Link PubMed
- Bhuyan, D.J.*, Alsherbiny, M.A., Perera, S., Low, M., Basu, A., Devi, O.A., Barooah, M.S., Li, C.G., and Papoutsis, K. (2019): The Odyssey of Bioactive Compounds in Avocado (Persea Americana) and Their Health Benefits. Antioxidants 8(10):426. https://doi.org/10.3390/antiox8100426 Link (Open Access) PubMed
2018
- Basu A., Dydowiczová A., Čtveráčková L., Jaša L., Trosko J. E., Bláha L., Babica P.* (2018): Assessment of hepatotoxic potential of cyanobacterial toxins using 3D in vitro model of adult human liver stem cells. Environmental Science and Technology 52 (17):10078–10088. https://doi.org/10.1021/acs.est.8b02291 Link PubMed
- Raška J., Čtveráčková L., Dydowiczová A., Sovadinová I., Bláha L, Babica P.* (2018): Tumor-promoting cyanotoxin microcystin-LR does not induce procarcinogenic events in adult human liver stem cells. Toxicology and Applied Pharmacology 345:103-113. https://doi.org/10.1016/j.taap.2018.03.011 Link PubMed
- Mikula P., Mlnaříková M, Takahashi H., Babica P., Kuroda K., Bláha L., Sovadinová I.* (2018): Branched poly(ethylene imine)s as anti-algal and anti-cyanobacterial agents with selective flocculation behavior to cyanobacteria over algae. Macromolecular Bioscience 18:1800187. https://doi.org/10.1002/mabi.201800187 Link PubMed [***Check the BACK COVER!***]
2017
- Sharma A., Bányiová K., Babica P., El Yamani N., Collins A. R., Čupr P.* (2017): Different DNA damage response of cis and trans isomers of commonly used UV filter after the exposure on adult human liver stem cells and human lymphoblastoid cells. Science of the Total Environment 593-594:18-26. https://doi.org/10.1016/j.scitotenv.2017.03.043 Link PubMed
- Addico G. N. D.*, Hardege J. D., Kohoutek J., deGraft-Johnson K.A.A., Babica P. (2017): Cyanobacteria and cyanotoxin contamination in untreated and treated drinking water in Ghana. Advances in Oceanography and Limnology 8(1):92-106. https://doi.org/10.4081/aiol.2017.6323 Link (Open Access)
- Sovadinová I.*, Babica P., Adamovský O., Alpatova A., Tarabara V., Upham B., Bláha L. (2017): Chlorination and ozonation differentially reduced the microcystin content and tumour promoting activity of a complex cyanobacterial extract. Advances in Oceanography and Limnology 8(1):107-120. https://doi.org/10.4081/aiol.2017.6342 Link (Open Access)
- Stoyneva-Gaertner M. P.*, Descy J.-P., Latli A., Uzunov B., Pavlova V., Bratanova Z., Babica P., Maršálek B., Meriluoto J., Spoof L. (2017): Assessment of cyanoprokaryote blooms and of cyanotoxins in Bulgaria in a 15-years period (2000-2015). Advances in Oceanography and Limnology 8(1):131-152. https://doi.org/10.4081/aiol.2017.6320 Link (Open Access)
2016
- Kollár P.*, Šmejkal K., Salmonová H., Vlková E., Lepšová-Skácelová O., Balounová Z., Rajchard J., Cvačka J., Jaša L., Babica P., Pazourek J. (2016): Assessment of chemical impact of invasive bryozoan Pectinatella magnifica on the environment. Cytotoxicity and antimicrobial activity of Pectinatella magnifica extracts. Molecules 21(11):1476. https://doi.org/10.3390/molecules21111476 Link (Open Access) PubMed
- Babica P.*, Zurabian R., Kumar E.R., Chopra R., Mianecki M., Park J.-S., Jaša L., Trosko J., Upham B. (2016): Methoxychlor and vincolozolin induce rapid changes in intracellular and intercellular signaling in liver progenitor cells. Toxicological Sciences 153(1):174-85. https://doi.org/10.1093/toxsci/kfw114 Link PubMed
- Kubincová P., Novák J., Sovadinová I.*(2016): Acute systemic toxicity: Alternative in vivo and in vitro methods. Chemické listy 110:118–125 Link
2015
- Adamovsky O.*, Moosová Z., Pekarová M., Basu A., Babica P., Švihalková-Šindlerová L., Kubala L., Bláha L. (2015): Immunomodulatory potency of microcystin, an important water polluting cyanobacterial toxin. Environmental Science and Technology 49(20):12457–12464. https://doi.org/10.1021/acs.est.5b02049 Link PubMed
- Sovadinová I., Babica P., Boke H., Kumar E. R., Wilke A., Park J. S., Trosko J. E., Upham B.* (2015): Phosphatidylcholine specific phospholipase C dysregulation of gap junctional intercellular communication, a robust cellular response to environmental toxicants, and prevention by resveratrol. PLoS One 10(5): e0124454. https://doi.org/10.1371/journal.pone.0124454 Link (Open Access) PubMed
- Taha S. T.*, Han H., Chang S.-R., Sovadinová I., Kuroda K., Langford R.M., Clarkson B.H. (2015): Nano/micro fluorhydroxyapatite crystal pastes in the treatment of dentin hypersensitivity: An in vitro study. Clinical Oral Investigations 19: 1921–1930. https://doi.org/10.1007/s00784-015-1427-2 Link PubMed
- Steuer A., Schmidt A., Babica P., Kolb J.* (2015): Effects of nanosecond pulsed electric fields on cell-cell communication in a monolayer. IFMBE Proceedings 53:192-195. https://doi.org/10.1007/978-981-287-817-5 Link
2014
- Sovadinová I.*, Liedtke A., Schirmer K. (2014): Effects of clofibric acid alone and in combination with 17 beta-estradiol on mRNA abundance in primary hepatocytes isolated from rainbow trout. Toxicology In Vitro 28: 1106–1116. https://doi.org/10.1016/j.tiv.2014.05.002 Link PubMed
2013
- Osgood R. O., Upham B. L., Hill T., Helms K. L., Velmurugan K., Babica P., Bauer A. K.* (2013): Polycyclic aromatic hydrocarbon-induced signaling events relevant to inflammation and tumorigenesis in lung cells are dependent on molecular structure. PLoS One 8(6): e65150. https://doi.org/10.1371/journal.pone.0065150 Link (Open Access) PubMed
Book Chapters
2021
- Kaushik P., Basu A., Dhankhar M. (2021): Synthesis of Nanomaterials and Nanostructures. In: Chemical Methods for Processing Nanomaterials (Ed.: Singh, V. N.), p. 38-47, CRC Press-Taylor & Francis group (ISBN 978-0-367-08588-9, eBook ISBN 9780429023187). Link
2017
- Bhuyan D. J.*, Basu A. (2017): Phenolic compounds: Potential Health Benefits and Toxicity. In: Utilisation of Bioactive Compounds from Agricultural and Food Production Waste (Ed.: Quan V. Vuong), p. 27-59, CRC Press (ISBN 9781498741316). Link
2016
2014
- Maršálek B.*, Babica P. (2014): Optical sensors for detection of cyanobacteria. In: Encyclopedia of Aquatic Ecotoxicology (Eds.: Férard, J.F. and Blaise, C.), p. 805-814. Springer (ISBN-10: 9400750404, ISBN-13: 978-9400750401). Link