Sabina Váńová succesfully defended her diploma thesis and passed the state exams yesterday. She graduated Summa Cum Laude and completed her master's degree program in Ecotoxicology at RECETOX, which makes her the most recent SECANTOX research group Alumni. Congratulations, Sabina, we gonna miss you so much! Pavel BBC
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A new paper has been accepted for publication in Nutrition and Cancer journal. The paper focuses on the ability of various chemopreventive and anticancer agents to prevent in vitro inhibition of gap junctional intercellular communication (GJIC) induced by environmental toxicants and tumor promoters. It has been found that chemopreventive agents commonly block effects of GJIC inhibitors. Such activity may not only represent a crucial mechanism contributing to the beneficial effects of the well-recognized dietary or pharmaceutical chemopreventive agents, but it can be utilized as an endpoint in a high throughput in vitro screening for novel chemopreventive and anticancer chemicals. The study has been a result of the research project "Novel in vitro approach for identification of chemopreventive effects and mechanisms of phytochemicals" hosted by Institute of Botany (Department of Experimental Phycology and Ecotoxicology), and implemented in collaboration with Prof. Brad L. Upham and Prof. James E. Trosko (Michigan State University) and also SECANTOX research group of RECETOX (Pavel Babica, Lucie Čtveráčková and Zuzana Lenčešová): Babica, P.*, Čtveráčková, L., Lenčešová, Z., Trosko, J. E., Upham, B. L. (2016): Chemopreventive agents attenuate rapid inhibition of gap junctional intercellular communication induced by environmental toxicants. Nutrition and Cancer 68(5):827-837 Full-text (Open Access from this Link) PubMed Pavel BBC
Tomáš Jambor will spend the next two months with SECANTOX research group at RECETOX. Tomáš is a Ph.D. student of Molecular Biology at Slovak University of Agriculture (Nitra, Slovakia), where he works on his dissertation thesis "Identification of action endocrine disruptors on the steroidogenesis in Leydig cells". Tomáš is coming to RECETOX within a "Freemovers" program and he will work here under supervision of Iva Sovadinová and Petra Macíková, focusing primarily on the effects of endocrine disrupting chemicals octylphenol and nonylphenol on the in vitro cultures of Leydig somatic testicular cells. Welcome Tomáš and good luck! Pavel BBC
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