There are couple upcoming local events and lectures, where results of our research will be presented: "Ecotox" group seminar, Jan 31, 9AM, Lecture room RCX1, Pavilion A29, Campus Bohunice, Brno: Honza Raška will present about the recent ESTIV course on "Applied In Vitro Toxicology" he attended. Then, he is going to present about the study focusing on the effects of cyanobacterial toxins on the different types of hepatic cells obtained by in vitro differentiation of human embryonic stem cells. "Ecotox" group seminar, Feb 7, 9AM, Lecture room RCX1, Pavilion A29, Campus Bohunice, Brno: Lucka Čtveráčková will present about her completed Erasmus+ project at ISPA (Lecce, Italy), where she studied in vitro effects of extracts from the zooxanthellate jellyfish Cotylorhiza tuberculata on normal and transformed rat liver epithelial cell lines. Diploma thesis defence, Feb 8, 9AM, Lecture room RCX1, Pavilion A29, Campus Bohunice, Brno: Veronika Musilová will defend her M.Sc. degree thesis titled "Hepatotoxic and hepatocarcinogenic effects of chemicals in spheroid cell cultures". Doctoral Conference in Chemistry, Feb 10, 9AM-6:30PM, Rm#132, Pavilion A11, Campus Bohunice, Brno: Libor Jaša will present a poster on his research of passive sampling applications in monitoring of cyanobacterial toxins. Mark your calendars! Pavel BBC
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Two project proposals of SECANTOX group members were approved for a funding this month. Czech Science Foundation (GACR) will support a three-year junior-researcher project supervised by Dr. Petra Labohá, who is going to study inhalation exposure to toxic cyanobacteria and its effects on human health. Furthermore, Amrita Basu will be working on an FRMU project focusing on the innovation of education at RECETOX, namely preparation of an online portal for students of Ecotoxicology programme. Congratulations! Pavel BBC
Pavel BBC
Pavel BBC
Pavel BBC
A paper on the effects of nanosecond pulsed electric fields (nsPEFs) has been accepted for publication in Bioelectrochemistry journal. The paper was a result of collaboration between Prof. Juergen F. Kolb, Anna Steuer and Anke Schmidt at the Institute for Plasma Science and Technology, INP Greifswald (Germany), and RECETOX, Masaryk University (Czech Rep.), represented by Pavel Babica and Petra Labohá (a former postdoctoral researcher at Prof. Kolb's lab). The paper is the very first report on the modulations of gap junctional intercellular communication by nsPEFs, which is a very perspective tool being developed and tested for different biomedical applications, such as cancer therapy or wound healing. nsPEF treatments were inducing rapid, pronounced but reversible inhibition of GJIC in vitro accompanied by disassembly of connexin plaques and activation of mitogen-activated protein kinases. Modulations of GJIC by nsPEF might contribute to its biological effects, and could be utilized to further develop more efficient or specific nsPEF treatments. Steuer, A., Schmidt, A., Labohá, P., Babica, P., Kolb, J.F.* (2016): Transient suppression of gap junctional intercellular communication after exposure to 100-nanosecond pulsed electric fields. Bioelectrochemistry 112:33-46 UPDATE: Full-text PubMed Pavel BBC
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